The Role of Early Life Environmental Risk Factors in Parkinson Disease: What Is the Evidence?

@inproceedings{Logroscino2005TheRO,
  title={The Role of Early Life Environmental Risk Factors in Parkinson Disease: What Is the Evidence?},
  author={Giancarlo Logroscino},
  booktitle={Environmental health perspectives},
  year={2005}
}
Parkinson disease (PD) is of unknown but presumably multifactorial etiology. Neuropathologic studies and animal models show that exposure to environmental neurotoxicants can determine progressive damage in the substantia nigra many years before the onset of clinical parkinsonism. Therefore, PD, like other neurologic diseases related to aging, may be determined by exposures present in the environment early during the life span or even during pregnancy. Recent epidemiologic studies have focused… CONTINUE READING
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Molecular pathways of neurodegeneration in Parkinson ’ s disease

  • M DawsonT, VL Dawson
  • Science
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