The Role of E2F3 in the Macrophage Assisted Metastasis of Breast Cancer

Abstract

Many studies have shown that macrophages play a critical role in metastasis within the tumor microenvironment. The aim of this study was to shed more light on the particular role of macrophages, and how the cell cycle transcription factor E2F3 affects tumor development and tumor metastasis. MMTV-PyMT was used to induce tumors in the mammary glands of female… (More)

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9 Figures and Tables