The Role of Dust Mites in Allergy

  title={The Role of Dust Mites in Allergy},
  author={Jeffrey D. Miller},
  journal={Clinical Reviews in Allergy \& Immunology},
  • Jeffrey D. Miller
  • Published 23 June 2018
  • Biology
  • Clinical Reviews in Allergy & Immunology
House dust mites are an unsurpassed cause of atopic sensitization and allergic illness throughout the world. The major allergenic dust mites Dermatophagoides pteronyssinus, Dermatophagoides farinae, Euroglyphus maynei, and Blomia tropicalis are eight-legged members of the Arachnid class. Their approximately 3-month lifespan comprises egg, larval, protonymph, tritonymph, and adult stages, with adults, about one fourth to one third of a millimeter in size, being at the threshold of visibility… 
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A novel allergen, Der f 38 binding to TLR4, is characterized and its role as an inducer of allergy is unveiled, shedding light on the pathogenic mechanisms of allergy to HDM.


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Home Environmental Interventions for House Dust Mite.
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A striking relationship between exposure to environmental allergens and atopic sensitization is illustrated with schoolchildren living in the Alps, where exposure to HDM is low, compared with those living at sea level, where it is high.
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