The Role of DNA Methylation in Invertebrates: Developmental Regulation or Genome Defense?

@article{Regev1998TheRO,
  title={The Role of DNA Methylation in Invertebrates: Developmental Regulation or Genome Defense?},
  author={Aviv Regev and Marion J. Lamb and Eva Jablonka},
  journal={Molecular Biology and Evolution},
  year={1998},
  volume={15},
  pages={880-891}
}
Cytosine methylation is widely distributed in multicellular organisms. We present a comprehensive survey of the existing data on the phylogenetic distribution of DNA methylation in invertebrates, together with new data for the crustacean Penaeus semisulcatus, the annelid Aporrectodea caliginosa trapezoides, and the parasitic platyhelminth Schistosoma mansoni. Two alternative hypotheses addressing the function of cytosine methylation in invertebrates are evaluated: (1) cytosine methylation is an… Expand

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