The Role of Corticotropin-releasing Hormone ( Crh ) in Stressor-induced Alterations of Sleep in the Rat

@inproceedings{Chang2002TheRO,
  title={The Role of Corticotropin-releasing Hormone ( Crh ) in Stressor-induced Alterations of Sleep in the Rat},
  author={Fang-Chia Chang and Mark R. Opp},
  year={2002}
}
Corticotropin-releasing hormone (CRH) mediates responses to a variety of stressors. We subjected rats to a one hour period of an acute stressor, physical restraint, and determined the impact on subsequent sleep-wake behavior. Restraint at the beginning of the light period, but not the dark period, increased waking and reduced rapid eye movements sleep (REMS) without dramatically altering slow wave sleep (SWS). Electroencephalogram (EEG) slow wave activity during SWS and brain temperature were… CONTINUE READING

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