The Role of Complex Formation and Deleterious Mutations for the Stability of RNA-Like Replicator Systems

  title={The Role of Complex Formation and Deleterious Mutations for the Stability of RNA-Like Replicator Systems},
  author={Nobuto Takeuchi and Paulien Hogeweg},
  journal={Journal of Molecular Evolution},
In the RNA world hypothesis, RNA(-like) self-replicators are suggested as the central player of prebiotic evolution. However, there is a serious problem in the evolution of complexity in such replicators, i.e., the problem of parasites. Parasites, which are replicated by catalytic replicators (catalysts), but do not replicate the others, can destroy a whole replicator system by exploitation. Recently, a theoretical study underlined complex formation between replicators—an often neglected but… 

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Group selection of early replicators and the origin of life.

The origin of replicators and reproducers

  • E. Szathmáry
  • Biology
    Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2006
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