The Role of Collectins and Galectins in Lung Innate Immune Defense

  title={The Role of Collectins and Galectins in Lung Innate Immune Defense},
  author={Cristina Casals and Mar{\'i}a Asunci{\'o}n Campanero-Rhodes and Bel{\'e}n Garc{\'i}a-Fojeda and Dolores Sol{\'i}s},
  booktitle={Front. Immunol.},
Different families of endogenous lectins use complementary defense strategies against pathogens. They may recognize non-self glycans typically found on pathogens and/or host glycans. The collectin and galectin families are prominent examples of these two lectin categories. Collectins are C-type lectins that contain a carbohydrate recognition domain and a collagen-like domain. Members of this group include surfactant protein A (SP-A) and D (SP-D), secreted by the alveolar epithelium to the… CONTINUE READING
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