The Role of Cardiac Tissue Alignment in Modulating Electrical Function

@article{Chung2007TheRO,
  title={The Role of Cardiac Tissue Alignment in Modulating Electrical Function},
  author={Chiung-yin Chung and Harold Bien and Emilia Entcheva},
  journal={Journal of Cardiovascular Electrophysiology},
  year={2007},
  volume={18}
}
Introduction: Most cardiac arrhythmias are associated with pathology‐triggered ion channel remodeling. However, multicellular effects, for example, exaggerated anisotropy and altered cell‐to‐cell coupling, can also indirectly affect action potential morphology and electrical stability via changed electrotonus. These changes are particularly relevant in structural heart disease, including hypertrophy and infarction. Recent computational studies showed that electrotonus factors into stability by… 
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77 Citations
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Methods Citations
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77 Citations

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