The Role of Cannabinoids in Neuroanatomic Alterations in Cannabis Users

  title={The Role of Cannabinoids in Neuroanatomic Alterations in Cannabis Users},
  author={Valentina Lorenzetti and Nadia Solowij and Murat Y{\"u}cel},
  journal={Biological Psychiatry},
The past few decades have seen a marked change in the composition of commonly smoked cannabis. These changes primarily involve an increase of the psychoactive compound ∆(9)-tetrahydrocannabinol (THC) and a decrease of the potentially therapeutic compound cannabidiol (CBD). This altered composition of cannabis may be linked to persistent neuroanatomic alterations typically seen in regular cannabis users. In this review, we summarize recent findings from human structural neuroimaging… CONTINUE READING
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Marijuana and brain health: Hippocampal injury, protection and recovery. Presented at Organization of the Human Brain Mapping

  • M Yücel, V Lorenzetti, V Suo, A Zalesky, A Fornito, F Fernandez
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