The Role of CREB in Depression and Antidepressant Treatment

@article{Blendy2006TheRO,
  title={The Role of CREB in Depression and Antidepressant Treatment},
  author={Julie A. Blendy},
  journal={Biological Psychiatry},
  year={2006},
  volume={59},
  pages={1144-1150}
}
  • J. Blendy
  • Published 15 June 2006
  • Medicine, Psychology
  • Biological Psychiatry
Major depressive disorder is a severe clinical problem across the globe, with a lifetime risk of 10%-30% for women and 7%-15% for men. The World Health Organization ranks major depression at the top of the list in terms of disease burden, and this burden is expected to rise in the next decade as the prevalence of the disorder grows. Since the late 1950s, a wide range of antidepressant medications targeting the monoamine systems has been available to alleviate the symptoms of major depressive… Expand
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