The Role of Autophagy in Aging

  title={The Role of Autophagy in Aging},
  author={E. Bergamini and G. Cavallini and A. Donati and Z. Gori},
  journal={Annals of the New York Academy of Sciences},
  • E. Bergamini, G. Cavallini, +1 author Z. Gori
  • Published 2007
  • Medicine, Biology
  • Annals of the New York Academy of Sciences
  • Abstract:  Aging denotes a postmaturational deterioration of cells and organisms with the passage of time, an increased vulnerability to challenges and prevalence of age‐associated diseases, and a decreased ability to survive. Causes of this deterioration may be found in an enhanced production of reactive oxygen species (ROS) and oxidative damage and incomplete “housekeeping.” Caloric restriction is the most robust anti‐aging intervention known so far. Similar beneficial effects on median and… CONTINUE READING
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