The Role of Autophagy in Aging

@article{Bergamini2007TheRO,
  title={The Role of Autophagy in Aging},
  author={Ettore Bergamini and Gabriella Cavallini and Alessio Donati and Zina Gori},
  journal={Annals of the New York Academy of Sciences},
  year={2007},
  volume={1114}
}
Abstract:  Aging denotes a postmaturational deterioration of cells and organisms with the passage of time, an increased vulnerability to challenges and prevalence of age‐associated diseases, and a decreased ability to survive. Causes of this deterioration may be found in an enhanced production of reactive oxygen species (ROS) and oxidative damage and incomplete “housekeeping.” Caloric restriction is the most robust anti‐aging intervention known so far. Similar beneficial effects on median and… 

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