The Role of AMPK in the Regulation of Skeletal Muscle Size, Hypertrophy, and Regeneration

@article{Thomson2018TheRO,
  title={The Role of AMPK in the Regulation of Skeletal Muscle Size, Hypertrophy, and Regeneration},
  author={D. M. Thomson},
  journal={International Journal of Molecular Sciences},
  year={2018},
  volume={19}
}
  • D. M. Thomson
  • Published 2018
  • Biology, Medicine
  • International Journal of Molecular Sciences
  • AMPK (5’-adenosine monophosphate-activated protein kinase) is heavily involved in skeletal muscle metabolic control through its regulation of many downstream targets. Because of their effects on anabolic and catabolic cellular processes, AMPK plays an important role in the control of skeletal muscle development and growth. In this review, the effects of AMPK signaling, and those of its upstream activator, liver kinase B1 (LKB1), on skeletal muscle growth and atrophy are reviewed. The effect of… CONTINUE READING
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