The Role and Metabolism of Sulfatide in the Nervous System

@article{Eckhardt2008TheRA,
  title={The Role and Metabolism of Sulfatide in the Nervous System},
  author={Matthias Eckhardt},
  journal={Molecular Neurobiology},
  year={2008},
  volume={37},
  pages={93-103}
}
3-O-sulfogalactosylceramide or sulfatide is a major component of the myelin sheath in the central and peripheral nervous system. The examination of mice deficient in the sulfatide-synthesizing enzyme, cerebroside sulfotransferase, provided new insight into the role of sulfatide in the differentiation of myelinating cells, formation of the paranodal junction, and myelin maintenance. Although in general regarded as a marker for oligodendrocytes and Schwann cells, sulfatide is also present in… CONTINUE READING
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