The RodA hydrophobin on Aspergillus fumigatus spores masks dectin-1- and dectin-2-dependent responses and enhances fungal survival in vivo.

@article{Carrion2013TheRH,
  title={The RodA hydrophobin on Aspergillus fumigatus spores masks dectin-1- and dectin-2-dependent responses and enhances fungal survival in vivo.},
  author={Steven de Jesus Carrion and Sixto M. Leal and Mahmoud Afif Ghannoum and Vishukumar Aimanianda and J P Latg{\'e} and Eric Pearlman},
  journal={Journal of immunology},
  year={2013},
  volume={191 5},
  pages={
          2581-8
        }
}
Aspergillus and Fusarium species are important causes of fungal infections worldwide. Airborne spores (conidia) of these filamentous fungi express a surface protein that confers hydrophobicity (hydrophobin) and covers cell wall components that would otherwise induce a host immune cell response. Using a mutant Aspergillus fumigatus strain (ΔrodA) that does not express the RodA hydrophobin, and Aspergillus and Fusarium conidia from clinical isolates that were treated with hydrofluoric acid (which… CONTINUE READING

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