The Risks and Benefits of Chemical Fumigation in the Health Care Environment

  title={The Risks and Benefits of Chemical Fumigation in the Health Care Environment},
  author={George Byrns and Thomas P. Fuller},
  journal={Journal of Occupational and Environmental Hygiene},
  pages={104 - 112}
  • G. Byrns, T. Fuller
  • Published 19 January 2011
  • Medicine
  • Journal of Occupational and Environmental Hygiene
Fumigation of hospital rooms with high concentrations of toxic chemicals has been proposed to reduce microbial agents on hospital surfaces and to control infections. Chemical fumigation has been used effectively in other areas, such as building decontamination after bioterrorism events, in agriculture, and in residential structures. However, even in these situations, there have been incidents where fumigants have escaped, causing illness and death to exposed workers and the public. Before… 
The uses and limitations of a hand-held germicidal ultraviolet wand for surface disinfection
This research demonstrates that UV-C was efficacious under optimal conditions, a direct beam exposure, and a short target distance, however, there are limitations when used in non-optimal conditions.
The Hitchhiker’s Guide to Hydrogen Peroxide Fumigation, Part 1: Introduction to Hydrogen Peroxide Fumigation
An overview of different fumigation systems based on hydrogen peroxide on the market and their technical requirements is presented and can be used as a guide to establish an effective fumigate system in a laboratory or an animal facility setting.
Effect of low-dose gaseous ozone on pathogenic bacteria
A single topical application by nebulization of a low ozone dose completely inhibited the growth of all potentially pathogenic bacterial strains with known resistance to antimicrobial agents.
Generation and Measurement of Chlorine Dioxide Gas at Extremely Low Concentrations in a Living Room: Implications for Preventing Airborne Microbial Infectious Diseases
The results advance progress toward using low concentration ClO2 gas to prevent airborne infectious diseases such as influenza by demonstrating that the gas concentrations measured in a room using the gas analyzer are accurate and reproducible.
Methodology to reduce formaldehyde exposure during laboratory fumigation
This model protocol would be a valuable training tool for any individual that may be required to undertake genuine formaldehyde fumigations and is outlined to reduce worker exposure to formaldehyde during essential fumigation training.
Alternative Room Disinfection Modalities – Pros and Cons
It is hypothesized that both fumigation and UV irradiation are capable of killing microorganisms; however, it is uncertain whether the benefits in terms of overall hospital patient infection rates outweigh the risks and costs associated with these methods.
Photolysis Driven Indoor Air Chemistry Following Cleaning of Hospital Wards.
Risks of photochemical formation of high concentrations of hydroxyl radicals, hydroperoxy radicals, organic peroxy radicals and chlorine radicals, which can form harmful reaction products when exposed to chemicals commonly found in indoor air, are reported.
A Comparative Study of Operation Theatre Disinfection by Fumigation Using Different Compounds
A comparative study of operation theatre disinfection by fumigation using different compounds. Background and Objective: Objective of this study was i) to evaluate the efficacy of formalin and


Effect of Gaseous Chlorine Dioxide on Indoor Microbial Contaminants
Traditional and modern techniques for bioaerosol enumeration were used to evaluate the relative efficiency of gaseous chlorine dioxide (ClO2) in reducing the indoor microbial contamination under field and laboratory conditions and found that the culturable bacteria and fungi were decreased at least 85% after the ClO2 application.
Identifying Opportunities to Enhance Environmental Cleaning in 23 Acute Care Hospitals
Significant opportunities in all participating hospitals to improve the cleaning of frequently touched objects in the patient's immediate environment are identified to improve cleaning and disinfection practices in healthcare institutions.
Investigation of gaseous ozone for MRSA decontamination of hospital side-rooms.
Adverse Human Health Effects Associated with Molds in the Indoor Environment
Current scientific evidence does not support the proposition that human health has been adversely affected by inhaled mycotoxins in home, school, or office environments, and levels of exposure in the indoor environment, dose-response data in animals, and dose-rate considerations suggest that delivery by the inhalation route of a toxic dose of mycotoxin in the indoors environment is highly unlikely at best.
Effect of Chlorine Dioxide Gas on Fungi and Mycotoxins Associated with Sick Building Syndrome
Data show that chlorine dioxide gas can be effective to a degree as a fumigant for the inactivation of certain fungal colonies, that the perithecia of C. globosum can play a slightly protective role for the ascospores and that S. chartarum, while affected by the fumigation treatment, still remains toxic.
Impact of Hydrogen Peroxide Vapor Room Decontamination on Clostridium difficile Environmental Contamination and Transmission in a Healthcare Setting
HPV decontamination was efficacious in eradicating C. difficile from contaminated surfaces and the incidence of nosocomial CDAD was significantly lower during the intervention period than during the preintervention period.
Comparison of the Efficacy of a Hydrogen Peroxide Dry-Mist Disinfection System and Sodium Hypochlorite Solution for Eradication of Clostridium difficile Spores
In situ experiments indicate that the hydrogen peroxide dry-mist disinfection system is significantly more effective than 0.5% sodium hypochlorite solution at eradicating С difficile spores and might represent a new alternative for disinfecting the rooms of patients with C.difficile infection.
Environmental control to reduce transmission of Clostridium difficile.
Unbuffered 1:10 hypochlorite solution is effective in decreasing patients' risk of developing CDAD in areas where CDAD is highly endemic, and presumed mechanisms include reducing the environmental burden and the potential for C. difficile transmission among susceptible patients.