The Rho1p exchange factor Rgf1p signals upstream from the Pmk1 mitogen-activated protein kinase pathway in fission yeast.

@article{Garcia2008TheRE,
  title={The Rho1p exchange factor Rgf1p signals upstream from the Pmk1 mitogen-activated protein kinase pathway in fission yeast.},
  author={Patr{\'i}cia Garcia and Virginia Tajadura and Yolanda S{\'a}nchez},
  journal={Molecular biology of the cell},
  year={2008},
  volume={20 2},
  pages={
          721-31
        }
}
The Schizosaccharomyces pombe exchange factor Rgf1p specifically regulates Rho1p during polarized growth. Rgf1p activates the beta-glucan synthase (GS) complex containing the catalytic subunit Bgs4p and is involved in the activation of growth at the second end, a transition that requires actin reorganization. In this work, we investigated Rgf1p signaling and observed that Rgf1p acted upstream from the Pck2p-Pmk1p MAPK signaling pathway. We noted that Rgf1p and calcineurin play antagonistic… CONTINUE READING

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Mechanosensation Dynamically Coordinates Polar Growth and Cell Wall Assembly to Promote Cell Survival.

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Negative functional interaction between cell integrity MAPK pathway and Rho1 GTPase in fission yeast.

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