The Rhizobium meliloti groELc locus is required for regulation of early nod genes by the transcription activator NodD.

@article{Ogawa1995TheRM,
  title={The Rhizobium meliloti groELc locus is required for regulation of early nod genes by the transcription activator NodD.},
  author={Junko Ogawa and Sharon Rugel Long},
  journal={Genes & development},
  year={1995},
  volume={9 6},
  pages={
          714-29
        }
}
The molecular chaperones related to GroEL (hsp60, cpn60) interact with partially folded proteins and appear to assist them to attain active and correctly folded conformation. They are required for cell viability but are probably more important for some processes than for others. Through a random genetic search to find loci that are required for expression of the Rhizobium meliloti nod (nodulation) genes, we isolated a mutant (B4) defective in luteolin-dependent activation of nod gene expression… CONTINUE READING
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