The Response of Canine Coronary Vascular Resistance to Local Alterations in Coronary Arterial Pco,


The effect of hypercapnia on coronary vascular resistance (CVR) was studied in seven open-chest dogs. Coronary blood flow was supplied to the cannulated left main coronary artery from the femoral artery by a precision pump. Coronary arterial Pco, was locally controlled with a small membrane oxygenator in the coronary perfusion circuit. Each Pco, change was… (More)


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