The Research of Technique on Fabricating Hydrogel Scaffolds for Cartilage Tissue Engineering Based on Stereo-lithography

@article{Linzhong2010TheRO,
  title={The Research of Technique on Fabricating Hydrogel Scaffolds for Cartilage Tissue Engineering Based on Stereo-lithography},
  author={Zhu Linzhong and L. Qin and Lu You and Bian Weiguo and L. Dichen and Jin Zhong-min},
  journal={2010 International Conference on Digital Manufacturing \& Automation},
  year={2010},
  volume={2},
  pages={782-784}
}
Based on stereo-lithography, the polyacrylamide hydrogel scaffolds with controlled accurate internal structures were fabricated. The structure accuracy of the scaffolds was evaluated by the size measurement compared with the CAD model. The mechanical property evaluation showed that the hydrogel compressive modulus of elasticity reached 4.54MPa, which was similar to that of the articular cartilage, therefore meeting the basic requirements of cartilage tissue engineering. The technique based on… Expand
4 Citations

Figures and Tables from this paper

Additive manufacturing techniques for scaffold-based cartilage tissue engineering
Articular cartilage damage is of great concern as it creates chronic pain and reduction of joint movement, leading to osteoarthritis. In current treatments, the resulting healing tissues lackExpand
3D Printing and Biofabrication for Load Bearing Tissue Engineering.
  • C. Jeong, A. Atala
  • Engineering, Medicine
  • Advances in experimental medicine and biology
  • 2015
TLDR
A topically focused review regarding the fundamental concepts, state of the art, and perspectives of this new technology and field of biofabrication and 3D bioprinting, specifically focused on tissue engineering of load bearing tissues such as bone, cartilage, osteochondral and dental tissue engineering. Expand
The status and challenges of replicating the mechanical properties of connective tissues using additive manufacturing.
TLDR
This review aims to provide an update on the current status of AM to mimic the mechanical properties of CTs, with focus on arterial tissue, articular cartilage and bone, from the perspective of printing platforms, biomaterial properties, and topological design. Expand

References

SHOWING 1-10 OF 10 REFERENCES
Development of Three-Dimensional Alginate Encapsulated Chondrocyte Hybrid Scaffold Using Microstereolithography
Hydrogels are useful materials because of their chemical similarity to extracellular matrix and their ability to rapidly diffuse hydrophilic nutrients and metabolites. Using rapid prototypingExpand
Defining Design Targets for Tissue Engineering Scaffolds
Biological tissues are extremely complex three-dimensional (3D) structures with concomitant complicated mechanical function and mass transport characteristics. Tissue engineering seeks toExpand
Direct fabrication process of ceramics based on stereolithography
This paper presents a novel direct ceramic shaping process-ceramic stereolithography by applying stereolithography in the ceramic shaping process.Through investigation based on experiments,it wereExpand
Stereolithography of Three-Dimensional Bioactive Poly(Ethylene Glycol) Constructs with Encapsulated Cells
TLDR
The results presented here indicate that the use of SL and photocross linkable biomaterials, such as photocrosslinkable PEG, appears feasible for fabricating complex bioactive scaffolds with living cells for a variety of important tissue engineering applications. Expand
Micro-stereolithography photopolymer solidification patterns for various laser beam exposure conditions
Micro-stereolithography is a novel micro-manufacturing process that fabricates 3D microstructures by solidifying the photopolymer using a UV laser in a layer-by-layer fashion. In this paper,Expand
Rapid Prototyping & Manufacturing: Fundamentals of Stereolithography
This reference provides complete coverage of a major new technology that generates physical objects directly from a graphical computer database. Known as "Rapid Prototyping and Manufacturing" (RP&M),Expand
etal; Direct fabrication process of ceramics based on stereolithography [J
  • Journal of Plasticity engineering,
  • 2009
Development of Three-Dimensional Alginate Encapsulated Chondrocyte Hybrid Scaffold Using Micro-stereolithography
  • Journal of Manufacturing Science and Engineering
  • 2008
Mann , and Ryan B . Wicker ; Stereolithography of Three - Dimensional Bioactive Poly ( Ethylene Glycol ) Constructs with Encapsulated Cells [ J ]
  • 2006
Fundamental Processes