The Relationship between Serotonergic Function and the Psychopathy Checklist: Screening Version

@article{Dolan2003TheRB,
  title={The Relationship between Serotonergic Function and the Psychopathy Checklist: Screening Version},
  author={Mairead C. Dolan and Ian Muir Anderson},
  journal={Journal of Psychopharmacology},
  year={2003},
  volume={17},
  pages={216 - 222}
}
Reduced serotonergic (5-HT) neurotransmission has been reported in impulsive and aggressive personality disordered and offender samples. What is not clear is the relationship between 5-HT function and the North American construct of psychopathy assessed using the Psychopathy Checklist and its derivatives, which emphasizes the core interpersonal/affective as well as behavioural components of this syndrome. Fifty-one DSM-III-R personality disordered offenders who had a dynamic assessment of 5-HT… 

Figures and Tables from this paper

Analysis of monoaminergic genes, childhood abuse, and dimensions of psychopathy.
TLDR
It is found that the emotional deficits characterizing the affective factor of psychopathy, as measured by the Psychopathy Checklist: Screening Version, were highest among carriers of the 5-HTT long allele, and the impulsive and irresponsible lifestyle features of Psychopathy were higher among low-activity than high-activity MAO-A carriers.
A bifactorial solution to the Psychopathy Checklist: Screening Version in a sample of civil psychiatric patients.
TLDR
A bifactor model, including two general factors (interpersonal-affective and antisocial-lifestyle), and four subordinate factors, provided the best fit to the data in a sample of civil psychiatric patients.
Serotonin (5-HT) augmentation reduces provoked aggression associated with primary psychopathy traits.
TLDR
Results indicated that primary psychopathy (but not secondary psychopathy) was related to aggressive responding to provocation, and 5- HT augmentation attenuated this effect, supporting the notion that aggressive responding associated with primary psychopathic traits may be due in part to 5-HT dysregulation.
The neuropsychology of prefrontal function in antisocial personality disordered offenders with varying degrees of psychopathy
  • M. Dolan
  • Psychology, Medicine
    Psychological Medicine
  • 2011
TLDR
Offenders with ASPD displayed subtle impairments on executive function tasks of planning ability and set shifting and behavioural inhibition compared to HCs, but among the offenders with ASD there was no significant association between executive function impairment and scores on the measure of psychopathy.
Psychometric Properties in Forensic Application of the Screening Version of the Psychopathy Checklist
TLDR
This review examines the psychometric properties of the PCL: SV, specifically in relation to forensic samples, and evaluates its comparability with the full PCL-R, and engages with wider debate concerning the measurement of psychopathy.
Understanding the structure of the psychopathy checklist - revised: an exploration of methodological confusion.
TLDR
This paper examines the source of this confound, the purpose of the Psychopathy Checklist, and illustrates how inappropriate methods can mislead.
Serotonin transporter availability in impulsive aggressive personality disordered patients: a PET study with [11C]DASB.
The effects of sertraline on psychopathic traits
TLDR
Independent of their effects on depression, antidepressants increase adaptive traits traditionally observed in psychopathic individuals, such as social charm and interpersonal and physical boldness, and reduce other, more maladaptive, traits associated with psychopathy, including dysregulated impulsivity and externalization.
Assessing and Treating Psychopaths
The psychopathic individual is characterized by limited affective experiences, is known to act impulsively and often antisocially, but also seems calm and at ease in the presence of others (Cleckley,
...
...

References

SHOWING 1-10 OF 56 REFERENCES
Relationship between 5-HT function and impulsivity and aggression in male offenders with personality disorders.
TLDR
Reduced 5-HT function was found in offenders with DSM-III-R borderline personality disorders and those with a history of repeated self-harm or alcohol misuse, and the 5- HT function was inversely correlated more strongly with impulsivity than with aggression.
Impulsiveness and the prolactin response to d-fenfluramine
TLDR
This study provides some support to the hypothesis that reduced serotonin function contributes to high trait impulsiveness and is not restricted to behaviourally extreme populations.
Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior.
TLDR
It is suggested that reduced central serotonergic function is present in a subgroup of patients with major affective and/or personality disorder and is associated with history of suicide attempt in patients with either disorder, but with impulsive aggression in Patients with personality disorder only.
Selective alteration of personality and social behavior by serotonergic intervention.
TLDR
Central serotonergic function may modulate a dimension of normal personality characterized by reduced negative affective experience and increased affiliative behavior even in the absence of baseline clinical depression or other psychopathology.
Psychopathy : theory, research, and implications for society
1. The Alvor Advanced Study Institute R.D. Hare. 2. Psychopathy Across Cultures D.J. Cooke. 3. Psychopathy and Normal Personality T.A. Widiger. 4. The Phenotypic and Genotypic Structure of
Biological contributions to crime causation
I. Psychophysiological Contributions.- 1 Psychophysiology and Crime: Theory and Data.- 2 Evoked Potentials and Antisocial Behavior.- 3 EEG Topography in Patients with Aggressive Violent Behavior.-
Impulsivity and Aggression
Partial table of contents: PHENOMENOLOGY. Measurements of Impulsivity and Aggression (P. Bech & M. Mak). The Epidemiology of Aggression (L. Robins). NEUROBIOLOGY. Biological Studies of Impulsivity,
The psychopathic individual: a lack of responsiveness to distress cues?
TLDR
The psychophysiological responsiveness of psychopathic individuals to distress cues and to threatening and neutral stimuli is investigated and the results are interpreted within the Violence Inhibition Mechanism model of the psychopathic individual.
...
...