The Relationship between Condom Use and Herpes Simplex Virus Acquisition

@article{Wald2005TheRB,
  title={The Relationship between Condom Use and Herpes Simplex Virus Acquisition},
  author={Anna Wald and Andria Langenberg and Elizabeth M. Krantz and John M. Douglas and H. Hunter Handsfield and Richard P Dicarlo and Adaora A. Adimora and Allen E. Izu and Rhoda Ashley Morrow and Lawrence Corey},
  journal={Annals of Internal Medicine},
  year={2005},
  volume={143},
  pages={707-713}
}
Context We need other means to reduce the risk for transmitting genital herpes (herpes simplex virus type 2 [HSV-2]). Are condoms effective? Content In a trial of an ineffective HSV-2 vaccine, 1843 participants were divided into 3 groups according to the frequency of condom use (for 0% to 25%, 25% to 75%, and >75% to 100% of sexual acts). Frequent condom users had fewer HSV-2 infections. Compared with participants in the next lowest category, participants in a category had a 26% lower risk for… Expand
A pooled analysis of the effect of condoms in preventing HSV-2 acquisition.
TLDR
Although the magnitude of protection was not as large as has been observed with other STIs, it was found that condoms offer moderate protection against HSV-2 acquisition in men and women. Expand
Risk Factors for Incident Herpes Simplex Type 2 Virus Infection Among Women Attending a Sexually Transmitted Disease Clinic
TLDR
Acquisition of HSV-2 infection among study participants was higher than previous estimates for adult female sexually transmitted disease clinic attendees, and no protective effect for condoms was demonstrated. Expand
Case-Crossover Analysis of Condom Use and Herpes Simplex Virus Type 2 Acquisition
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The case-crossover design offers increased control of individual-level confounders, and was thus used with the aim of producing a more accurate estimate of the effect of condom use on HSV-2 acquisition. Expand
Epidemiological Impact of a Genital Herpes Type 2 Vaccine for Young Females
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Computer simulation shows that an adolescent-only vaccination program may be effective in eliminating HSV-2 disease, however, the success of extinction greatly depends on the level of vaccine uptake, the vaccine efficacy, the age of sexual maturity and safe sex practices. Expand
Predictors of herpes simplex virus type 2 prevalence and incidence among bar and hotel workers in Moshi, Tanzania.
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Investigation among female bar and hotel workers in Moshi, Tanzania found incident HSV-2 infection was independently associated with HIV infection, younger age of sexual initiation, ethnicity, alcohol consumption, and having a male partner with other sexual partners. Expand
Does Frequency of Genital Herpes Recurrences Predict Risk of Transmission? Further Analysis of the Valacyclovir Transmission Study
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Clinical assessment of HSV-2 disease severity as defined by the frequency of genital herpes recurrences does not predict the risk of transmission to sexual partners, and frequency of recurrence is not helpful in identifying persons who are most likely to transmit HSv-2. Expand
Prevalence and predictors of herpes simplex virus type 2 infection among female sex workers in Yunnan Province, China
TLDR
This study identifies a very high prevalence of HSV-2 infections among FSWs in Yunnan Province, with only a few who reported a prior history of genital herpes. Expand
Prevalence of specific herpes simplex virus-2 antibodies and associated factors in women of a rural town of Colombia.
TLDR
The overall seroprevalence rate of women of Pueblorrico, Colombia, is lower than that reported in other Latin American countries especially in women>45 years, and the difference may be explained by higher prevalence of condom use in this population or lower exposure to herpes infection in male as well as females in the past. Expand
Asymptomatic shedding of herpes simplex virus 1 and 2: implications for prevention of transmission.
  • G. Mertz
  • Medicine
  • The Journal of infectious diseases
  • 2008
It is counterintuitive that sexual transmission of herpes simplex virus (HSV) more commonly results from contact during a short episode of asymptomatic shedding than from contact with lesions. AfterExpand
Seroprevalence of Herpes Simplex Virus Type 2 and Characteristics Associated With Undiagnosed Infection: New York City, 2004
TLDR
HSV-2 is highly prevalent and largely undiagnosed in New York City; seroprevalence varies by subgroup; targeted HSV- 2 screening, counseling and treatment may help reduce transmission of HSv-2 and human immunodeficiency virus. Expand
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