The Relationship Between Metformin and Serum Prostate‐Specific Antigen Levels

@inproceedings{Jayalath2016TheRB,
  title={The Relationship Between Metformin and Serum Prostate‐Specific Antigen Levels},
  author={Viranda H. Jayalath and Christopher Ireland and Neil E. Fleshner and Robert J Hamilton and David J A Jenkins},
  booktitle={The Prostate},
  year={2016}
}
BACKGROUND Metformin is the first-line oral antihyperglycemic of choice for individuals with type 2 diabetes. Recent evidence supports a role for metformin in prostate cancer chemoprotection. However, whether metformin indeed influences prostate biology is unknown. We aimed to study the association between metformin and serum prostate-specific antigen (PSA) levels-the primary prostate cancer biomarker. METHODS We conducted a cross-sectional study of 326 prostate cancer-free men with type 2… CONTINUE READING
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