The Relationship Between Iron Storage and Anaemia

@article{Davidson1952TheRB,
  title={The Relationship Between Iron Storage and Anaemia},
  author={William Mark Davidson and R. F. Jennison},
  journal={Journal of Clinical Pathology},
  year={1952},
  volume={5},
  pages={281 - 285}
}
cells. The ironprotein complex, ferritin, isdifficult todemonstrate asitoccursasa diffuse non-particulate material, buthaemosiderin canreadily beseenas itforms golden granules whichgive aniron reaction withtheordinary histochemical methods. Ithasbeensuggested that ofthese twocompounds ferritin isthemorelabile andreadily takes partin thesynthesis ofhaemoglobin, whereas haemosiderin isthereserve store formed, either astheresult of denaturation ofhaemoglobin orbypolymerization whenthereisadequate… 
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What is the evidence for gender differences in ferritin and haemoglobin?
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References

SHOWING 1-6 OF 6 REFERENCES
Iron metabolism; the pathophysiology of iron storage.
TLDR
This sequence of events, whether following excessive iron absorption or parenteral iron administration is believed to be responsible for the clinical and pathologic picture of hemochromatosis.
Serum Iron in Normal Women
  • S. Dahl
  • Medicine
    British medical journal
  • 1948
TLDR
As shown in the present experiments, when examining the useful action of any factor on the process of ageing it is dangerous not to take into consideration the harmful effects which are present simultaneously with the useful ones.
Acta haemat., Basel, 5, 19
  • J. Lab. cin. Med
  • 1948