The Relationship Between Gastric Myoelectric Activity and SCN5A Mutation Suggesting Sodium Channelopathy in Patients With Brugada Syndrome and Functional Dyspepsia - A Pilot Study

@inproceedings{Jung2012TheRB,
  title={The Relationship Between Gastric Myoelectric Activity and SCN5A Mutation Suggesting Sodium Channelopathy in Patients With Brugada Syndrome and Functional Dyspepsia - A Pilot Study},
  author={Kyo Tae Jung and Hyojin Park and Jie-Hyun Kim and Dong-jik Shin and Bo Young Joung and M G Lee and Yang Soo Jang},
  booktitle={Journal of neurogastroenterology and motility},
  year={2012}
}
BACKGROUND/AIMS SCN5A encodes the cardiac-specific Na(V)1.5 sodium channel, and Brugada syndrome is a cardiac conduction disorder associated with sodium channel α-subunit (SCN5A) mutation. The SCN5A-encoded Na(V)1.5 channel is also found on gastrointestinal smooth muscle and interstitial cells of Cajal. We investigated the relationship between functional dyspepsia (FD) and SCN5A mutation to evaluate sodium channelopathy in FD. METHODS Patients with Brugada syndrome or FD were examined using… CONTINUE READING
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