The Relationship Between FST and the Frequency of the Most Frequent Allele

@inproceedings{Jakobsson2013TheRB,
  title={The Relationship Between FST and the Frequency of the Most Frequent Allele},
  author={Mattias Jakobsson and Michael D. Edge and Noah A. Rosenberg},
  booktitle={Genetics},
  year={2013}
}
F(ST) is frequently used as a summary of genetic differentiation among groups. It has been suggested that F(ST) depends on the allele frequencies at a locus, as it exhibits a variety of peculiar properties related to genetic diversity: higher values for biallelic single-nucleotide polymorphisms (SNPs) than for multiallelic microsatellites, low values among high-diversity populations viewed as substantially distinct, and low values for populations that differ primarily in their profiles of rare… CONTINUE READING
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