The Relationship Between Ambient Air Pollution and Acute Ischemic Stroke: A Time‐Stratified Case‐Crossover Study in a City‐State With Seasonal Exposure to the Southeast Asian Haze Problem

  title={The Relationship Between Ambient Air Pollution and Acute Ischemic Stroke: A Time‐Stratified Case‐Crossover Study in a City‐State With Seasonal Exposure to the Southeast Asian Haze Problem},
  author={Andrew Fu Wah Ho and Huili Zheng and Deidre Anne De Silva and Win Wah and Arul Earnest and Yee Hau Pang and Zhenjia Xie and Pin Pin Maeve Pek and Nan Liu and Yih Yng Ng and Ting Hway Wong and Ling Li Foo and Marcus Eng Hock Ong},
  journal={Annals of Emergency Medicine},
Study objective: Studies are divided on the short‐term association of air pollution with stroke. Singapore is exposed to seasonal transboundary haze. We aim to investigate the association between air pollution and stroke incidence in Singapore. Methods: We performed a time‐stratified case‐crossover analysis on all ischemic stroke cases reported to the Singapore Stroke Registry from 2010 to 2015. Exposure on days was compared with control days on which exposure did not occur. Control days were… Expand
Time‐Stratified Case Crossover Study of the Association of Outdoor Ambient Air Pollution With the Risk of Acute Myocardial Infarction in the Context of Seasonal Exposure to the Southeast Asian Haze Problem
An effect of short‐term air pollution on AMI incidence, especially non–ST‐segment–elevation myocardial infarction and inpatient AMI, is found, which has public health implications for primary prevention and emergency health services during haze. Expand
The Relationship Between Air Pollution and All-Cause Mortality in Singapore
  • Ho, Zheng, +9 authors Ong
  • Environmental Science
  • 2019
Ambient air pollution is a risk factor for both acute and chronic diseases and poses serious health threats to the world population. We aim to study the relationship between air pollution andExpand
Association between air pollution exposure and diabetic retinopathy among diabetics.
The higher particulate matter exposure, the higher is the DR risk in patients with DM and the association of ambient air pollution exposure with DR risk is determined. Expand
Impact of Air Pollution and Seasonal Haze on Neurological Conditions.
Air pollution is associated with increased risk of certain common neurological disorders, and more specific studies are needed to investigate the impact of seasonal haze on neurological conditions in Southeast Asia. Expand
Impact of Air Pollution and Trans-Boundary Haze on Nation-Wide Emergency Department Visits and Hospital Admissions in Singapore.
Investigation of the impact of air pollution on nation-wide emergency department (ED) visits and hospital admissions to public hospitals in Singapore found increased PSI was not associated with increase in total ED visits andospital admissions, but was associated with increased ED visitsand hospital admissions for respiratory conditions in Singapore. Expand
Acute Health Impacts of the Southeast Asian Transboundary Haze Problem—A Review
  • K. H. Cheong, N. Ngiam, +6 authors A. Ho
  • Geography, Medicine
  • International journal of environmental research and public health
  • 2019
This review paper aims to synthesize current research efforts on the impact of the Southeast Asian transboundary haze on acute aspects of public health and to guide policy-making and international strategy in minimizing theimpact of seasonal haze in Southeast Asia. Expand
Ambient air pollution and the risk of ischaemic and haemorrhagic stroke.
An outlook on new research opportunities, such as those provided by the decreased levels of air pollution due to the current COVID-19 pandemic, are provided. Expand
Weather and Temporal Factors Associated with Use of Emergency Medical Services
EMS responses increased with rising temperature and following rain and snow, and these findings may assist in planning by EMS agencies and emergency departments to identify periods of greatest resource utilization. Expand
The impact of public participation in environmental behavior on haze pollution and public health in China
Abstract This study extends the STIRPAT model based on Grossman’s health production function and uses Chinese provincial panel data from 2000 to 2017 to examine regional differences in the impacts ofExpand
PM2.5, PM2.5-related air pollutants, health hazards and impacts on respiratory and cardiovascular disorders and diseases: systematic review and meta-analysis
The objective of the study is to perform a critical review, exploration, and strong summary of the relationships between personal and ambient concentrations of mainly particulate matter with diameterExpand


The impact of short-term exposure to air pollutants on the onset of out-of-hospital cardiac arrest: A systematic review and meta-analysis.
The current evidence confirmed the associations between short-term exposure to PM2.5, PM10 and O3 and a high risk of OHCA, with the strongest association being observed for PM2-5.5. Expand
Residential Proximity to Major Roadways and Risk of Incident Ischemic Stroke in NOMAS (The Northern Manhattan Study)
Evidence is found that within-city variation in residential proximity to major roadway is associated with higher risk of ischemic stroke, with the association remaining only among participants not currently smokers. Expand
Air pollution and stroke - an overview of the evidence base.
  • R. Maheswaran
  • Medicine
  • Spatial and spatio-temporal epidemiology
  • 2016
There is already sufficient evidence to support consideration of reduction in air pollution as a preventative measure to reduce the stroke burden globally, according to this work. Expand
A systematic review of air pollution and incidence of out-of-hospital cardiac arrest
The association of air pollution with the occurrence of out-of-hospital cardiac arrest (OHCA) was examined to suggest an increased risk of OHCA with air pollution exposure from PM2.5 and ozone. Expand
Air Pollution and Stroke
Findings that the strength of this association is stronger in low and middle income countries where air pollution is projected to rise as a result of rapid industrialisation are of particular concern. Expand
Ozone and cardiovascular injury
The epidemiological, clinical and experimental evidence of the effects of ozone on cardiovascular diseases, including the correlation between ozone level and occurrence of acute myocardial infarction, is explored. Expand
Cardiovascular effects of air pollution.
Experimental studies indicate that some pollutants have more harmful cardiovascular effects, such as combustion-derived PM2.5 and ultrafine particles, and promotion of safer air quality appears to be a new challenge in cardiovascular disease prevention. Expand
Ambient air pollution and stroke.
A large body of evidence supports the association between ambient air pollution exposure and increased cardiovascular mortality and morbidity, but only recently have several studies specifically demonstrated an association with increased stroke risk. Expand
Countrywide Stroke Incidence, Subtypes, Management and Outcome in a Multiethnic Asian Population: The Singapore Stroke Registry — Methodology
The Singapore Stroke Registry is a countrywide registry of risk factors, stroke subtypes, management and outcome of incident and recurrent stroke in multiethnic Singapore, and has many features of an ‘ideal’ incidence study. Expand
Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement From the American Heart Association
It is the opinion of the writing group that the overall evidence is consistent with a causal relationship between PM2.5 exposure and cardiovascular morbidity and mortality. Expand