The Redox Function of APE1 Is Involved in the Differentiation Process of Stem Cells toward a Neuronal Cell Fate

@inproceedings{Domenis2014TheRF,
  title={The Redox Function of APE1 Is Involved in the Differentiation Process of Stem Cells toward a Neuronal Cell Fate},
  author={Rossana Domenis and Natascha Bergamin and Giuseppe Gianfranceschi and Carlo Vascotto and Milena Romanello and Silvia Rigo and Giovanna Vagnarelli and Massimo Faggiani and Piercamillo Parodi and Mark R Kelley and Carlo Alberto Beltrami and Daniela Cesselli and Gianluca Tell and Antonio Paolo Beltrami},
  booktitle={PloS one},
  year={2014}
}
UNLABELLED Low-to-moderate levels of reactive oxygen species (ROS) govern different steps of neurogenesis via molecular pathways that have been decrypted only partially. Although it has been postulated that redox-sensitive molecules are involved in neuronal differentiation, the molecular bases for this process have not been elucidated yet. The aim of this work was therefore to study the role played by the redox-sensitive, multifunctional protein APE1/Ref-1 (APE1) in the differentiation process… CONTINUE READING
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