The Redox Code

  title={The Redox Code},
  author={D. H. P. Jones and Helmut Sies},
  booktitle={Antioxidants & redox signaling},
SIGNIFICANCE The redox code is a set of principles that defines the positioning of the nicotinamide adenine dinucleotide (NAD, NADP) and thiol/disulfide and other redox systems as well as the thiol redox proteome in space and time in biological systems. The code is richly elaborated in an oxygen-dependent life, where activation/deactivation cycles involving O₂ and H₂O₂ contribute to spatiotemporal organization for differentiation, development, and adaptation to the environment. Disruption of… CONTINUE READING
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