The Reading Frame BPLF1 of Epstein-Barr Virus: A Homologue of Herpes Simplex Virus Protein VP16

Abstract

The open reading frame BPLF1 of Epstein-Barr virus (EBV) shows homology to the Herpes simplex virus 1 (HSV1) protein VP16. This protein is a structural tegument component playing a pivotal role for HSV replication as trans-activator of viral immediate-early genes. An EBV gene with a comparable function has not been described so far. However, computer… (More)
DOI: 10.1023/B:VIRU.0000036387.39937.9b

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