The Rational Basis for Cancer Chemotherapy

  title={The Rational Basis for Cancer Chemotherapy},
  author={Branimir Sikic},
Modern cancer chemotherapy originated in the 1940s with the demonstration that nitrogen mustard possessed antitumor activity against human lymphomas and leukemias. Approximately 10 types of human cancer have 40 to 80% “cure” rates using chemotherapy alone or chemotherapy plus surgery or radiation (Table 55.1). For this purpose cure is defined as the… CONTINUE READING