The Rat IgGFcγBP and Muc2 C-Terminal Domains and TFF3 in Two Intestinal Mucus Layers Bind Together by Covalent Interaction

@article{Yu2011TheRI,
  title={The Rat IgGFcγBP and Muc2 C-Terminal Domains and TFF3 in Two Intestinal Mucus Layers Bind Together by Covalent Interaction},
  author={H. Yu and Yonghong He and X. Zhang and Z. Peng and Y. Yang and R. Zhu and J. Bai and Y. Tian and X. Li and W. Chen and D. Fang and R. Wang},
  journal={PLoS ONE},
  year={2011},
  volume={6}
}
  • H. Yu, Yonghong He, +9 authors R. Wang
  • Published 2011
  • Chemistry, Medicine
  • PLoS ONE
  • Background The secreted proteins from goblet cells compose the intestinal mucus. The aims of this study were to determine how they exist in two intestinal mucus layers. Methodology/Principal Findings The intestinal mucosa was fixed with Carnoy solution and immunostained. Mucus from the loose layer, the firm layer was gently suctioned or scraped, respectively, lysed in SDS sample buffer with or without DTT, then subjected to the western blotting of rTFF3, rIgGFcγBP or rMuc2. The non-reduced or… CONTINUE READING
    TFF Peptides Play a Role in the Immune Response Following Oral Infection of Mice with Toxoplasma Gondii
    14
    Effects of chronic Porphyromonas gingivalis lipopolysaccharide infusion on skeletal muscles in mice
    2
    Role of phosphodiesterase 4 expression in the Epac1 signaling‐dependent skeletal muscle hypertrophic action of clenbuterol
    9

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 32 REFERENCES
    Human intestinal TFF3 forms disulfide-linked heteromers with the mucus-associated FCGBP protein and is released by hydrogen sulfide.
    62
    Intestinal Goblet Cells and Mucins in Health and Disease: Recent Insights and Progress
    766
    Cleavage in the GDPH sequence of the C-terminal cysteine-rich part of the human MUC5AC mucin.
    48
    Distribution and partial characterisation of IgG Fc binding protein in various mucin producing cells and body fluids
    70