The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin.

Abstract

Cilia are microtubule-based organelles that are present on most cells and are required for normal tissue development and function. Defective cilia cause complex syndromes with multiple organ manifestations termed ciliopathies. A crucial step during ciliogenesis in multiciliated cells (MCCs) is the association of future basal bodies with the apical plasma… (More)
DOI: 10.1242/dev.112250

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Cite this paper

@article{Epting2015TheRR, title={The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin.}, author={Daniel Epting and Krasimir Slanchev and Christopher S. Boehlke and Sylvia G Hoff and Niki Tomas Loges and Takayuki Yasunaga and Lara Indorf and Sigrun Nestel and Soeren S. Lienkamp and Heymut Omran and eva K{\"{u}hn and Olaf Ronneberger and Gerd Walz and Albrecht Kramer-Zucker}, journal={Development}, year={2015}, volume={142 8}, pages={1553} }