The RSK family of kinases: emerging roles in cellular signalling

@article{Anjum2008TheRF,
  title={The RSK family of kinases: emerging roles in cellular signalling},
  author={Rana Anjum and John Blenis},
  journal={Nature Reviews Molecular Cell Biology},
  year={2008},
  volume={9},
  pages={747-758}
}
The 90 kDa ribosomal S6 kinase (RSK) family of proteins is a group of highly conserved Ser/Thr kinases that regulate diverse cellular processes, such as cell growth, cell motility, cell survival and cell proliferation. RSKs are downstream effectors of the Ras–extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signalling cascade. Significant advances in the field of RSK and ERK/MAPK signalling have occurred in the past few years, including biological insights and… CONTINUE READING
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