The RSC chromatin remodelling enzyme has a unique role in directing the accurate positioning of nucleosomes.

@article{Wippo2011TheRC,
  title={The RSC chromatin remodelling enzyme has a unique role in directing the accurate positioning of nucleosomes.},
  author={Christian J Wippo and Lars Israel and Shinya Watanabe and Andreas Hochheimer and Craig L. Peterson and Philipp Korber},
  journal={The EMBO journal},
  year={2011},
  volume={30 7},
  pages={1277-88}
}
Nucleosomes impede access to DNA. Therefore, nucleosome positioning is fundamental to genome regulation. Nevertheless, the molecular nucleosome positioning mechanisms are poorly understood. This is partly because in vitro reconstitution of in vivo-like nucleosome positions from purified components is mostly lacking, barring biochemical studies. Using a yeast extract in vitro reconstitution system that generates in vivo-like nucleosome patterns at S. cerevisiae loci, we find that the RSC… CONTINUE READING

From This Paper

Topics from this paper.
27 Citations
63 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 63 references

Similar Papers

Loading similar papers…