The ROS-generating oxidase Nox1 is required for epithelial restitution following colitis

Abstract

Accumulating evidence suggests that reactive oxygen species (ROS) generated by endogenous metabolic enzymes are involved in a variety of intracellular mechanisms. In particular, superoxide-generating NADPH oxidase (Nox) 1 is highly expressed in the colon and has been implicated in physiological and pathophysiological states of colon tissues. However, its… (More)
DOI: 10.1538/expanim.15-0127

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