The RNA exosome affects iron response and sensitivity to oxidative stress.

Abstract

RNA degradation plays important roles for maintaining temporal control and fidelity of gene expression, as well as processing of transcripts. In Saccharomyces cerevisiae the RNA exosome is a major 3'-to-5' exoribonuclease and also has an endonuclease domain of unknown function. Here we report a physiological role for the exosome in response to a stimulus… (More)
DOI: 10.1261/rna.043257.113

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