The RNA chaperone, Hfq, controls two luxR-type regulators and plays a key role in pathogenesis and production of antibiotics in Serratia sp. ATCC 39006.

@article{Wilf2011TheRC,
  title={The RNA chaperone, Hfq, controls two luxR-type regulators and plays a key role in pathogenesis and production of antibiotics in Serratia sp. ATCC 39006.},
  author={Nabil M. Wilf and Neil R. Williamson and Joshua P Ramsay and Simon Poulter and Kasia J Bandyra and George P. C. Salmond},
  journal={Environmental microbiology},
  year={2011},
  volume={13 10},
  pages={2649-66}
}
Serratia sp. ATCC 39006 (S39006) is a Gram-negative bacterium that is virulent in plant (potato) and animal (Caenorhabditis elegans) models. It produces two secondary metabolite antibiotics, a prodigiosin and a carbapenem, and the exoenzymes, pectate lyase and cellulase. A complex regulatory network that includes quorum sensing (QS) controls production of prodigiosin. While many aspects of the regulation of the metabolites and exoenzymes are well understood, the potential role in this network… CONTINUE READING