The RNA-binding protein Rrm4 is essential for polarity in Ustilago maydis and shuttles along microtubules.

  title={The RNA-binding protein Rrm4 is essential for polarity in Ustilago maydis and shuttles along microtubules.},
  author={Philip Becht and J. K{\"o}nig and Michael Feldbr{\"u}gge},
  journal={Journal of cell science},
  volume={119 Pt 23},
Formation of polar-growing hyphae is essential for infection by the plant pathogen Ustilago maydis. Here we observe that loss of RNA-recognition motif protein Rrm4 caused formation of abnormal hyphae. The insertion of septa at the distal pole was abolished and a significantly increased number of hyphae grew bipolarly. UV-crosslinking experiments revealed that Rrm4 bound RNA via its N-terminal RRMs and that its RNA-binding activity was substantially increased during filamentation. Rrm4 assembled… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 40 references

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P. Becht, E. Vollmeister, M. Feldbrügge
View 5 Excerpts
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View 4 Excerpts
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View 6 Excerpts
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EMBO J . • 2006
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