The RNA-binding protein Rrm4 is essential for polarity in Ustilago maydis and shuttles along microtubules.

@article{Becht2006TheRP,
  title={The RNA-binding protein Rrm4 is essential for polarity in Ustilago maydis and shuttles along microtubules.},
  author={Philip Becht and J. K{\"o}nig and Michael Feldbr{\"u}gge},
  journal={Journal of cell science},
  year={2006},
  volume={119 Pt 23},
  pages={
          4964-73
        }
}
Formation of polar-growing hyphae is essential for infection by the plant pathogen Ustilago maydis. Here we observe that loss of RNA-recognition motif protein Rrm4 caused formation of abnormal hyphae. The insertion of septa at the distal pole was abolished and a significantly increased number of hyphae grew bipolarly. UV-crosslinking experiments revealed that Rrm4 bound RNA via its N-terminal RRMs and that its RNA-binding activity was substantially increased during filamentation. Rrm4 assembled… CONTINUE READING
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