The RNA Polymerase II Machinery Structure Illuminates Function

@article{Woychik2002TheRP,
  title={The RNA Polymerase II Machinery Structure Illuminates Function},
  author={Nancy A. Woychik and Michael Hampsey},
  journal={Cell},
  year={2002},
  volume={108},
  pages={453-463}
}
Essential components of the eukaryotic transcription apparatus include RNA polymerase II, a common set of initiation factors, and a Mediator complex that transmits regulatory information to the enzyme. Insights into mechanisms of transcription have been gained by three-dimensional structures for many of these factors and their complexes, especially for yeast RNA polymerase II at atomic resolution.