The RECK gene and biological malignancy--its significance in angiogenesis and inhibition of matrix metalloproteinases.

@article{AlexiusLindgren2014TheRG,
  title={The RECK gene and biological malignancy--its significance in angiogenesis and inhibition of matrix metalloproteinases.},
  author={Michelle Alexius-Lindgren and Erika Andersson and Ingrid Lindstedt and Wilhelm Engstr{\"o}m},
  journal={Anticancer research},
  year={2014},
  volume={34 8},
  pages={3867-73}
}
The RECK (reversion-inducing cysteine-rich protein with Kazal motifs) gene is a relatively newly discovered gene with important implications in cancer biology. RECK is normally expressed in all cells of the body and has an important role in the balance between destructive and constructive features of the extracellular matrix (ECM). The RECK protein is a membrane-bound glycoprotein that inhibits matrix metalloproteinases with the function of breaking-down the ECM. There is a significant… CONTINUE READING