The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae.

@article{Weinert1988TheRG,
  title={The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae.},
  author={T. Weinert and L. Hartwell},
  journal={Science},
  year={1988},
  volume={241 4863},
  pages={
          317-22
        }
}
  • T. Weinert, L. Hartwell
  • Published 1988
  • Biology, Medicine
  • Science
  • Cell division is arrested in many organisms in response to DNA damage. Examinations of the genetic basis for this response in the yeast Saccharomyces cerevisiae indicate that the RAD9 gene product is essential for arrest of cell division induced by DNA damage. Wild-type haploid cells irradiated with x-rays either arrest or delay cell division in the G2 phase of the cell cycle. Irradiated G1 and M phase haploid cells arrest irreversibly in G2 and die, whereas irradiated G2 phase haploid cells… CONTINUE READING
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