The R148.3 Gene Modulates Caenorhabditis elegans Lifespan and Fat Metabolism

Abstract

Despite many advances, the molecular links between energy metabolism and longevity are not well understood. Here, we have used the nematode model Caenorhabditis elegans to study the role of the yet-uncharacterized gene R148.3 in fat accumulation and lifespan. In wild-type worms, a R148.3p::GFP reporter showed enhanced expression throughout life in the… (More)
DOI: 10.1534/g3.117.041681

Topics

5 Figures and Tables