The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release

@inproceedings{Brackman2016TheQS,
  title={The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release},
  author={Gilles Brackman and Koen Breyne and Riet De Rycke and Arno Vermote and Filip Van Nieuwerburgh and Evelyne Meyer and Serge van Calenbergh and Tom Coenye},
  booktitle={Scientific reports},
  year={2016}
}
Treatment of Staphylococcus aureus infections has become increasingly challenging due to the rapid emergence and dissemination of methicillin-resistant strains. In addition, S. aureus reside within biofilms at the site of infection. Few novel antibacterial agents have been developed in recent years and their bacteriostatic or bactericidal activity results in selective pressure, inevitably inducing antimicrobial resistance. Consequently, innovative antimicrobials with other modes of action are… CONTINUE READING
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