The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger

Abstract

In response to infection and injury, the neutrophil population rapidly expands and then quickly re-establishes the basal state when inflammation resolves. The exact pathways governing neutrophil/macrophage lineage outputs from a common granulocyte-macrophage progenitor are still not completely understood. From a forward genetic screen in zebrafish, we… (More)
DOI: 10.1038/ncomms14911

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