The Psychobiology of Stress

@article{Kemeny2003ThePO,
  title={The Psychobiology of Stress},
  author={Margaret E. Kemeny},
  journal={Current Directions in Psychological Science},
  year={2003},
  volume={12},
  pages={124 - 129}
}
  • M. Kemeny
  • Published 1 August 2003
  • Psychology, Biology
  • Current Directions in Psychological Science
Stressful life experience can have significant effects on a variety of physiological systems, including the autonomic nervous system, the hypothalamic-pituitary-adrenal axis, and the immune system. These relationships can be bidirectional; for example, immune cell products can act on the brain, altering mood and cognition, potentially contributing to depression. Although acute physiological alterations may be adaptive in the short term, chronic or repeated provocation can result in damage to… 

Figures from this paper

Psychobiological responses to social threat: Evolution of a psychological model in psychoneuroimmunology
  • M. Kemeny
  • Psychology
    Brain, Behavior, and Immunity
  • 2009
An Examination of the Direct and Indirect Effects of Feedback Type on Cortisol levels
RABIDEAU, ERIN M., Ph.D., May 2015, Psychology An Examination of the Direct and Indirect Effects of Feedback Type on Cortisol Levels Director of Dissertation: Peggy M. Zoccola Although acute
Black sheep get the blues: A psychobiological model of social rejection and depression
Activation of the hypothalamic-pituitary adrenal axis in response to a verbal fluency task and associations with task performance
TLDR
It is concluded that a verbal fluency task acts like an acute stressor that induces a cortisol and a perceived stress response without the need for further stress components, and is a less time-consuming alternative to other stress tasks that can be used in field studies with little effort.
Biological and environmental factors associated with the stress response in infancy : the role of attachment and genetics
The importance of understanding which environmental and biological factors are involved in determining individual differences in physiological response to stress is widely recognized, as the impact
Subjective General Health and the Social Regulation of Hypothalamic Activity
TLDR
Higher self-ratings of general health corresponded with decreased hypothalamic activity during a task that blends threat with supportive handholding, suggesting that associations between social support and health are partly mediated through the social regulation of hypothalamic sensitivity to threat.
Elevated Cortisol Leaves Working Memory Unaffected in Both Men and Women
TLDR
Cross-study methodological differences account for reports describing sex differences in effects of stress on WM performance, and it is speculated that between-study variation in the magnitude of baseline cortisol levels might affect outcomes.
Emotional Pathways to the Biological Embodiment of Racial Discrimination Experiences
TLDR
Investigating whether NSE emotions are a pathway by which discrimination dysregulates HPA-axis functioning as measured by cortisol levels suggests that daily NSE and average negative emotions are important pathways by which racial discrimination gets under the skin, or is embodied, in stress biology.
Social-Evaluative Threat and Proinflammatory Cytokine Regulation
TLDR
stimulated production of the proinflammatory cytokine tumor necrosis factor-α (TNF-α) increased from baseline to poststressor in the SET condition, but was unchanged in the non-SET condition.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 24 REFERENCES
Social neuroscience: autonomic, neuroendocrine, and immune responses to stress.
TLDR
It is found that acute psychological stressors activate the sympathetic adrenomedullary system across individuals and affect immune function; and individuals characterized by high sympathetic cardiac reactivity to acute psychologicalstressors also show a relative activation of the hypothalamic pituitary adrenocortical system and altered immune function.
Social neuroscience: autonomic, neuroendocrine, and immune responses to stress.
TLDR
It is found that acute psychological stressors activate the sympathetic adrenomedullary system across individuals and affect immune function; and individuals characterized by high sympathetic cardiac reactivity to acute psychologicalstressors also show a relative activation of the hypothalamic pituitary adrenocortical system and altered immune function.
Affect, cognition, the immune system and health.
Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition.
TLDR
It is argued that activation of immune-brain pathways is important for understanding diverse phenomena related to stress such as depression and suppression of specific immunity.
Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition.
TLDR
It is argued that activation of immune-brain pathways is important for understanding diverse phenomena related to stress such as depression and suppression of specific immunity.
Complexities of Stress. (Book Reviews: Perturbing the Organism. The Biology of Stressful Experience.)
TLDR
This authoritative work is the first to analyze critically the entire range of research and theory on stress in animals and humans, from the earliest studies in the 1930s up to the present day, and supplies a new working definition and classification of stressful experience.
When the social self is threatened: shame, physiology, and health.
TLDR
It is demonstrated that acute threats to the social self increase proinflammatory cytokine activity and cortisol and that these changes occur in concert with shame, which support a stressor- and emotional response-specificity model for psychobiological and health research.
When the social self is threatened: shame, physiology, and health.
TLDR
It is demonstrated that acute threats to the social self increase proinflammatory cytokine activity and cortisol and that these changes occur in concert with shame, which support a stressor- and emotional response-specificity model for psychobiological and health research.
Chronic psychological stress and the regulation of pro-inflammatory cytokines: a glucocorticoid-resistance model.
  • G. Miller, Sheldon Cohen, A. Ritchey
  • Medicine, Biology
    Health psychology : official journal of the Division of Health Psychology, American Psychological Association
  • 2002
TLDR
There was evidence that chronic stress impaired the immune system's response to anti-inflammatory signals: the capacity of a synthetic glucocorticoid hormone to suppress in vitro production of the pro-inflammatory cytokine interleukin-6 was diminished among parents of cancer patients.
Chronic psychological stress and the regulation of pro-inflammatory cytokines: a glucocorticoid-resistance model.
  • G. Miller, Sheldon Cohen, A. Ritchey
  • Medicine, Biology
    Health psychology : official journal of the Division of Health Psychology, American Psychological Association
  • 2002
TLDR
There was evidence that chronic stress impaired the immune system's response to anti-inflammatory signals: the capacity of a synthetic glucocorticoid hormone to suppress in vitro production of the pro-inflammatory cytokine interleukin-6 was diminished among parents of cancer patients.
...
1
2
3
...