The Pseudomonas aeruginosa Transcriptome in Planktonic Cultures and Static Biofilms Using RNA Sequencing

@inproceedings{Doetsch2012ThePA,
  title={The Pseudomonas aeruginosa Transcriptome in Planktonic Cultures and Static Biofilms Using RNA Sequencing},
  author={Andreas Doetsch and Denitsa Eckweiler and Monika Schniederjans and Ariane Zimmermann and Vanessa K. Jensen and Maren Scharfe and Robert Geffers and S. H{\"a}u\ssler},
  booktitle={PloS one},
  year={2012}
}
In this study, we evaluated how gene expression differs in mature Pseudomonas aeruginosa biofilms as opposed to planktonic cells by the use of RNA sequencing technology that gives rise to both quantitative and qualitative information on the transcriptome. Although a large proportion of genes were consistently regulated in both the stationary phase and biofilm cultures as opposed to the late exponential growth phase cultures, the global biofilm gene expression pattern was clearly distinct… CONTINUE READING
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