The Protein-Folding Problem, 50 Years On
@article{Dill2012ThePP,
title={The Protein-Folding Problem, 50 Years On},
author={K. Dill and Justin L. MacCallum},
journal={Science},
year={2012},
volume={338},
pages={1042 - 1046}
}Protein Folding: Past and Future Fifty years ago the Nobel Prize in chemistry was awarded to Max Perutz and John Kendrew for determining the structure of globular proteins. Since first viewing their structure of myoglobin, scientists have sought to understand protein folding. Dill and MacCallum (p. 1042) review the progress that has been made on three central questions: What is the code that relates sequence to structure? How do proteins fold so fast? Can protein structure be computationally… CONTINUE READING
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