The Protective Role of Resveratrol in the Sodium Arsenite-Induced Oxidative Damage via Modulation of Intracellular GSH Homeostasis

@article{Chen2013ThePR,
  title={The Protective Role of Resveratrol in the Sodium Arsenite-Induced Oxidative Damage via Modulation of Intracellular GSH Homeostasis},
  author={Chengzhi Chen and Xuejun Jiang and Yanan Hu and Zunzhen Zhang},
  journal={Biological Trace Element Research},
  year={2013},
  volume={155},
  pages={119-131}
}
Sodium arsenite (NaAsO2) is a well-established environmental carcinogen that has been found to cause various human malignant tumors. Thus, how to prevent the deleterious effects caused by NaAsO2 has received widely concerns. Resveratrol (3,4′,5-trihydroxystilbene), a polyphenol found in numerous plant species, has recently been known as a natural and powerful antioxidant. However, whether resveratrol could attenuate the toxicity of NaAsO2 and its detailed mechanisms have not been reported. In… CONTINUE READING

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