The Protective Effects of Omega-3 Fatty Acids and Sesame Oil on Cyclosporine-A Induced Liver Apoptosis

Objective: Cyclosporine A (CsA) is the most effective and widely used immunosuppressant in solid organ transplantation and autoimmune diseases. Despite its benefits, the clinical use of CsA is limited by its nephrotoxic and hepatotoxic properties. Omega-3 fatty acids (O-3) comprise a family of unsaturated fatty acids that consist of α-linolenic acid… (More)