The Protective Effects of Areca catechu Extract on Cognition and Social Interaction Deficits in a Cuprizone-Induced Demyelination Model

@inproceedings{Adilijiang2015ThePE,
  title={The Protective Effects of Areca catechu Extract on Cognition and Social Interaction Deficits in a Cuprizone-Induced Demyelination Model},
  author={Abulimiti Adilijiang and Teng Guan and Jue He and Kelly Hartle and Wenqiang Wang and Xinmin Li},
  booktitle={Evidence-based complementary and alternative medicine : eCAM},
  year={2015}
}
Schizophrenia is a serious psychiatric illness with an unclear cause. One theory is that demyelination of white matter is one of the main pathological factors involved in the development of schizophrenia. The current study evaluated the protective effects of Areca catechu nut extract (ANE) on a cuprizone-induced demyelination mouse model. Two doses of ANE (1% and 2%) were administered orally in the diet for 8 weeks. Animals subjected to demyelination showed impaired spatial memory and less… CONTINUE READING

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